The five clearest signs of Xanax addiction are the eyes, slowed movement and speech, memory gaps, mood swings between doses, and preoccupation with the next dose. The eyes show it first: involuntary side to side eye movement, heavy drooping lids and a fixed glassy stare that appears regardless of sleep. Alprazolam (Xanax) is a Schedule IV benzodiazepine prescribed for anxiety and panic disorder. Alprazolam produces physical dependence even at the recommended dose, and the FDA label records that dependence risk rises above 4 mg daily and beyond 12 weeks of treatment.
Call 911 now if a person has taken Xanax with alcohol or opioids and is unresponsive, breathing slowly or turning blue. For a mental health or suicidal crisis, call or text 988 to reach the Suicide and Crisis Lifeline, or chat at 988lifeline.org. The service is free, confidential and available 24 hours a day, with Spanish-language and ASL access.
Highlights
- Xanax is one of the most addictive prescription medications available. The FDA label records that dependence risk rises above 4 mg daily and beyond 12 weeks of treatment
- The most visible physical sign of Xanax intoxication is the eyes, involuntary side to side eye movement, a heavy-lidded appearance, and a fixed, unfocused gaze
- Behavioral warning signs include slowed movement, memory problems, mood swings, and increasing social withdrawal
- Polysubstance use, particularly combining Xanax with alcohol, dramatically increases overdose risk and is a serious escalation sign
- Xanax withdrawal is medically dangerous and must never be attempted without clinical supervision
- The combination of low barrier to prescription access and rapid tolerance development makes Xanax one of the highest-risk medications for developing addiction
What Is Xanax and Why Is It Addictive?
Xanax is the brand name for alprazolam, a short-acting benzodiazepine prescribed for anxiety disorders, panic disorder and insomnia. Alprazolam enhances the effects of GABA (gamma-aminobutyric acid) in the brain, the brain’s primary inhibitory neurotransmitter, which produces sedation, muscle relaxation, reduced anxiety, and a sense of calm.
The same mechanism that makes Xanax effective for anxiety also makes it highly addictive. GABA enhancement produces a rapid, intense sense of relief and calm that the brain quickly learns to associate with the drug. As the brain adapts to alprazolam, the brain produces less GABA naturally. Without Xanax, a person feels more anxious, more agitated and less able to cope than before they started taking it. That rebound is the cycle of physical dependence.
Xanax is short-acting compared to other benzodiazepines like Valium (diazepam), which means its effects wear off quickly. The shorter duration accelerates tolerance and creates a cycle of use that progresses to addiction faster than longer-acting benzos. The FDA classifies alprazolam as a Schedule IV controlled substance due to its recognized abuse potential.
How Quickly Does Xanax Addiction Develop?
Xanax addiction develops in as little as four weeks of daily therapeutic use at prescribed doses. Abuse escalates this timeline significantly.
What Do Xanax Eyes Look Like?
“Xanax eyes” is one of the most searched phrases related to Xanax use, and for good reason. The eyes are the most immediately visible indicator that someone is intoxicated on Xanax or has recently taken a large dose.
There are 7 signs of Xanax use in the eyes:
- Involuntary side to side eye movement (nystagmus): Alprazolam produces jerking eye movements when a person tracks an object across their field of vision. The DSM-5-TR lists nystagmus among the diagnostic criteria for benzodiazepine intoxication. Pupil size stays normal, which separates benzodiazepine intoxication from opioid intoxication, where the pupils constrict to pinpoints.
- Heavy, drooping eyelids (ptosis): One of the most recognizable features. The eyelids appear heavy and partially closed, giving the person a half-awake appearance regardless of the time of day or how much sleep they have had.
- Glassy, unfocused appearance: The eyes look glassy or distant, and the gaze is fixed or slow to track movement.
- The “Xanax stare”: A fixed, glazed look in which the person looks at something without registering it. Xanax’s central nervous system depression slows visual processing and attention.
- Reduced blinking: Benzodiazepines slow reflex responses; a reduced blink rate, combined with a heavy-lidded appearance, gives the eyes a distinctly blank or empty quality.
- Bloodshot eyes: Prolonged Xanax use, particularly when combined with disrupted sleep, produces red or bloodshot eyes.
- Dry eyes: Xanax reduces secretions throughout the body, producing dry eyes and dry mouth together in regular users.
The eye signs are most pronounced immediately after taking a dose or after exceeding the prescribed amount. Xanax eye signs are not obvious in someone using a low, stable dose, but after escalated use or recreational misuse, the eye presentation is unmistakable to someone who knows what to look for.
What Are the Behavioral Signs of Xanax Addiction?
Behavioral signs are the first warning that someone close to you notices before they connect the change to Xanax use. Personality changes develop gradually, which makes them easy to attribute to stress, depression or “just getting older.”
There are 9 behavioral signs of Xanax addiction:
- Slowed movement and speech: Xanax suppresses the central nervous system, producing measurable slowing of physical responses, reflexes, and verbal processing. A person who was previously animated and quick-moving operates at a slower speed: slower to respond in conversation, slower to stand up or move around, slower to complete tasks.
- Sedation and excessive fatigue: The person is tired much of the time. They sleep longer than before, nap during the day, and fight sleep when awake. This is not ordinary tiredness; it is CNS-depressed sedation.
- Memory problems: Xanax impairs the formation of new memories (anterograde amnesia), particularly at higher doses. This is the same mechanism by which alcohol blocks memory formation. The person forgets conversations from hours earlier, misses appointments they agreed to, and has no recollection of events from the previous day. This is not normal forgetfulness.
- Sudden mood changes: Benzodiazepines produce rapid shifts between euphoria, calm and emotional volatility. A person who has recently taken Xanax is unusually relaxed, talkative and affectionate. Between doses, and increasingly as tolerance develops, they become irritable, anxious and difficult to engage.
- Increased anxiety when the drug wears off: Someone developing Xanax dependence experiences heightened anxiety between doses. This is the result of rebound, as the drug wears off, the suppressed nervous system rebounds and produces anxiety that feels worse than before treatment began. This reinforces continued use.
- Social withdrawal: As addiction progresses, the person withdraws from activities, relationships and responsibilities they previously valued. Social events that require sustained engagement become difficult to manage; isolation is easier.
- Secretiveness about medication: This shows as resistance to discussing how much Xanax they take, anger if asked about their prescription, and taking medication in private rather than openly.
- Slurred speech: At moderate to high doses, alprazolam impairs speech production in a manner similar to alcohol, producing slurred, slow, or difficult-to-follow speech.
- Coordination problems: The person stumbles, struggles with fine motor tasks and is physically unsteady. It is most noticeable in people who are normally well coordinated.
What Are the Physical Signs of Xanax Addiction?
Beyond the eyes, Xanax addiction shows in dry mouth, headaches, nausea and constipation, reduced libido, weight change, tremors between doses, pale skin and emotional blunting. There are 8 physical signs of Xanax addiction:
- Dry mouth: One of the most consistently reported physical effects. Regular Xanax users report persistent dry mouth, visible as constant sipping of water and dry, cracked lips.
- Headaches: Xanax produces headaches, particularly as a dose wears off or during periods of missed doses. Users who take Xanax daily develop chronic low-grade headaches that temporarily resolve after taking the drug, reinforcing continued use.
- Nausea and constipation: Both are documented side effects of alprazolam. Gastrointestinal effects are more pronounced in heavy users.
- Reduced libido and sexual dysfunction: This is a significant quality-of-life effect that patients search for and clinicians rarely raise. Xanax suppresses the central nervous system broadly, which includes suppression of sexual drive, arousal, and function. People taking Xanax regularly lose interest in sex, and men develop difficulty with erection and ejaculation. This effect is dose-dependent and reverses with discontinuation.
- Weight changes: Some users gain weight with chronic Xanax use, related to increased appetite and reduced physical activity due to sedation. Others lose weight, particularly if they are substituting Xanax for meals or disrupting normal eating patterns.
- Tremors or shakiness when not taking the drug: As the body becomes dependent, not having Xanax produces physical tremors and shakiness. This is a withdrawal sign and indicates established physical dependence.
- Pale or sallow skin: Reduced physical activity, poor nutrition and disrupted sleep dull the skin over time in chronic Xanax use.
How Does Xanax Change Personality?
One of the most distressing aspects of Xanax addiction for family members is the personality change. Families report that their loved one “isn’t themselves,” a description that captures something real about how chronic benzodiazepine use alters personality and emotional functioning.
There are 5 personality signs of Xanax addiction:
- Emotional blunting: Xanax suppresses both anxiety and emotional responsiveness broadly. A person on chronic Xanax is less emotionally present, less excited by things they used to enjoy, less engaged in relationships and less reactive to both positive and negative events.
- Loss of motivation: The sedating effects of Xanax create what some describe as an “emotional anesthesia,” everything feels equally manageable and equally unimportant. Goals, ambitions, and personal drive fade.
- Increased irritability between doses: The neurological rebound that occurs as Xanax wears off produces heightened anxiety and irritability that is disproportionate to circumstances. Family members describe walking on eggshells: the person is pleasant when medicated and difficult when not.
- Disinhibition: Like alcohol, Xanax reduces inhibition and judgment. The person says things and behaves in ways inconsistent with their normal character, including emotional outbursts, impulsive behavior and unusual frankness.
- Cognitive changes: Chronic benzodiazepine use impairs attention, executive function and processing speed. The person seems “foggy,” struggles to follow complex conversations and labors over decisions they once handled easily.
Are these personality changes permanent? Most cognitive and emotional effects of benzodiazepine use are reversible with discontinuation and adequate time for neurological recovery, but recovery takes months to years for heavy, long-term users.
How to Tell If Someone Is High on Xanax Right Now
Knowing the signs of active Xanax intoxication (being “high” or currently under the influence) is different from recognizing addiction patterns over time.
There are 8 signs that someone is high on Xanax right now:
- Heavy-lidded eyes with a glassy, unfocused appearance
- Slurred or slow speech
- Physical unsteadiness or poor coordination
- Unusual calmness, reduced anxiety, or euphoria
- Slow to respond to questions or stimuli
- Confusion or disorientation about where they are or what is happening
- Inappropriate drowsiness, appearing to fall asleep in conversation or while sitting
- Slowed breathing, in severe cases, is a medical emergency
Call 911 immediately if the person is unresponsive, cannot be roused, is breathing slowly and shallowly, or has turned blue around the lips. Benzodiazepine overdose, particularly when combined with alcohol or opioids, produces fatal respiratory depression.
What Happens When Xanax Is Combined With Other Substances?
Polysubstance use is one of the most serious escalation signs in Xanax addiction. The reason medical providers warn against mixing Xanax with alcohol is not precautionary; it is because the combination is among the most pharmacologically dangerous drug pairings.
Xanax and Alcohol
Both suppress the central nervous system. Combined, they produce a synergistic effect, not additive, but multiplicative, dramatically increasing the risk of respiratory depression, overdose, and death. Mixing Xanax with alcohol, even in amounts that feel moderate, raises the risk of slowed breathing, coma and death.
Regular drinking alongside Xanax is a serious warning sign of addiction, whether or not other signs are present.
Xanax and Opioids
The combination of benzodiazepines and opioids is responsible for a significant proportion of overdose deaths in the United States. The FDA issued a Black Box warning specifically about this combination. Both substances depress respiration via distinct mechanisms; together they produce respiratory arrest.
Xanax and Other Benzodiazepines
When a prescription is not sufficient to maintain the addiction, users supplement with street Xanax, other benzodiazepines, or counterfeit pills. Counterfeit “Xanax bars,” pressed pills sold on the street, contain illicit fentanyl and have been responsible for mass overdose events across the U.S.
There are 5 signs that someone has moved to street Xanax:
- Repeated early refills of the prescription
- Unexplained pills or pill bottles not matching their prescription
- Financial strain inconsistent with their income
- Secretiveness about their medication supply
- Purchases of what they claim is Xanax from people who are not pharmacies
Why Is Preoccupation With Xanax an Early Warning Sign?
Preoccupation with obtaining and using Xanax appears before the more dramatic signs of addiction. Identifying preoccupation early matters, because preoccupation marks the window when intervention is most effective.
There are 8 signs of Xanax preoccupation:
- Anxiety or agitation as the dose time approaches
- Repeated checking of pill supply, counting pills, worrying about running out
- Significant distress or panic at the prospect of not having Xanax available
- Requests for a prescription refill well before the refill is due
- Doctor shopping, visiting more than one provider to obtain additional prescriptions
- Research into how to obtain Xanax through non-prescription channels
- Organization of life around Xanax availability, with no travel or socializing without ensuring supply
- Doses taken early or more frequently than prescribed to prevent anticipated anxiety
How Does Xanax Addiction Damage Work, School and Relationships?
Xanax addiction creates a widening ripple of consequences that touch every area of daily functioning.
Xanax addiction shows up at work and in relationships in 5 ways:
- At work: The sedating effects of Xanax make sustained attention, quick decision-making, and task completion difficult. Absenteeism increases. Performance declines. Coworkers notice unexplained lapses in reliability and unusual behavior.
- At school: For adolescents and young adults, Xanax addiction dramatically impairs academic performance. Memory formation is critical to learning; Xanax’s amnesiac effects make retaining information from classes or studying extremely difficult. Attendance drops. Grades decline. Social relationships with non-using peers erode.
- Driving: Xanax impairs driving in a manner comparable to alcohol. Driving while taking Xanax, particularly at higher doses or in combination with alcohol, is illegal and dangerous. A DUI or a driving accident is the event that first exposes hidden Xanax abuse.
- Relationships: Family members describe living with a different person. The emotional blunting, memory problems, unreliability and personality changes Xanax addiction produces strain relationships across all domains, including romantic partnerships, friendships, and parenting relationships.
- Parenting: Parents with Xanax addiction are physically present but emotionally and cognitively unavailable to their children. That absence constitutes neglect. Courts and child protective services have become increasingly attentive to prescription drug misuse in households with children.
What Are the Signs of Xanax Addiction in Teens?
There are 8 warning signs of Xanax use in adolescents:
- Sudden academic decline without an obvious cause
- Withdrawal from activities, sports, or social groups they previously participated in
- New friend groups, particularly older peers
- Unexplained pills or pill containers
- “Xanax bars” are the rectangular 2mg tablets sold illicitly and discussed in teen social media
- Slurred speech or unusual drowsiness after school
- Mood changes are more dramatic than typical adolescent variation
- Money missing from family members’ wallets or unusual financial requests
Teen Xanax use is particularly dangerous because of the developing brain’s heightened vulnerability to benzodiazepine effects, and because counterfeit Xanax bars containing fentanyl are aggressively marketed through social media channels that teenagers use.
What Does Xanax Do Sexually?
Reduced libido and sexual dysfunction are among the least discussed effects of Xanax use, and among the most reported by patients. People searching this question are trying to understand what Xanax is doing to their body or their relationship.
Xanax suppresses sexual function through 4 mechanisms:
- Libido suppression: The broad CNS depression from alprazolam reduces sex drive. This occurs in both men and women, though men notice it more acutely due to the erection-dependent nature of male sexual response.
- Arousal difficulties: Xanax reduces physical sensitivity and slows arousal responses. Both men and women find it harder to become aroused and to reach orgasm while taking Xanax.
- Erectile dysfunction: Men taking Xanax regularly report difficulty achieving and maintaining erections. This is a pharmacological effect of the drug, not a separate medical condition.
- Ejaculatory delay or anorgasmia: Delayed ejaculation in men and difficulty reaching orgasm in women are documented effects of regular benzodiazepine use.
- Emotional disconnection during sex: The emotional blunting Xanax produces makes sexual intimacy feel distant or unimportant, even when physical capability is intact.
Sexual side effects are dose-dependent, and the effects intensify at higher doses and with longer duration of use. The effects improve with dose reduction or discontinuation, though recovery takes weeks to months.
Is Xanax Addictive? Understanding Dependence vs. Addiction
“Is Xanax addictive?” is one of the most searched questions in this topic area. The answer requires distinguishing between two related but different concepts.
Physical dependence means the body has adapted to the presence of Xanax and will experience withdrawal symptoms without it. Physical dependence develops in anyone who takes Xanax daily for four or more weeks, including patients who take it exactly as prescribed and have no history of addiction or substance misuse.
Addiction involves compulsive use despite negative consequences, loss of control over use, and continued use despite knowing it is harmful. Addiction involves both physical dependence and psychological patterns of craving and compulsive seeking.
Not everyone who develops physical dependence on Xanax develops addiction. Physical dependence makes stopping much harder, and people with a personal or family history of substance use disorders face a higher risk of progression to addiction.
There are 6 Xanax addiction risk factors:
- Personal or family history of addiction
- History of anxiety disorder (using Xanax to manage anxiety creates a self-reinforcing cycle)
- Untreated co-occurring depression
- History of trauma or PTSD
- Use of Xanax in doses higher than prescribed
- Use of Xanax in combination with alcohol
Sedative, Hypnotic, or Anxiolytic Use Disorder is the DSM-5 term for Xanax addiction. The DSM-5-TR criteria include taking more than intended, unsuccessful efforts to cut down, spending significant time obtaining or using the drug, and craving. The criteria also include failure to fulfill major obligations, and continued use despite the social and interpersonal problems the drug causes.
Why Does Stopping Xanax Require Medical Support?
Xanax withdrawal is one of the most medically dangerous withdrawal syndromes of any substance. Like alcohol withdrawal, benzodiazepine withdrawal produces seizures, status epilepticus (continuous seizures) and death, which is why stopping Xanax suddenly is unsafe.
There are 11 signs of Xanax withdrawal:
- Intense anxiety, worse than the pre-treatment baseline
- Tremors and shakiness
- Sweats
- Heart palpitations and rapid heart rate
- Insomnia
- Irritability and agitation
- Nausea and vomiting
- Headache
- Muscle pain and tension
- Confusion and cognitive impairment
- Seizures (this is the life-threatening risk)
Withdrawal is most severe in people who have used Xanax daily at high doses for extended periods, and in people who stop abruptly rather than tapering. Alprazolam clears fast. The FDA label puts its mean plasma elimination half-life at 11.2 hours, range 6.3 to 26.9 hours, so withdrawal symptoms surface within a day of the last dose.
Never attempt to stop Xanax suddenly without medical supervision. A medically supervised taper, gradually reducing the dose under clinical guidance and switching to a longer-acting benzodiazepine first, is the standard of care for Xanax discontinuation. Medical detox ensures withdrawal is managed safely and comfortably.
What Should You Do If You Recognize These Signs in Someone?
Recognizing the signs is the first step. The next question is what to do with that recognition.
There are 5 steps for approaching someone with Xanax addiction:
- Start with a direct, compassionate conversation: Choose a time when the person is sober, not intoxicated, not in withdrawal. Express concern in terms of what you have observed, not accusation or judgment. “I’ve noticed you seem much more tired lately, and I’ve been worried” is more productive than “I know you’re addicted.”
- Do not enable: Covering for missed work or school, providing money that funds drugs, minimizing the behavior to other family members, or ignoring signs out of discomfort; these actions protect the addiction, not the person.
- Set clear boundaries: Boundaries are not ultimatums or punishments; they are statements of what you will and will not do. “I love you, and I will support you in getting help, but I will not continue to excuse absences from work” is a boundary.
- Understand that professional treatment is required: Xanax addiction cannot be safely managed through willpower alone due to the medical dangers of withdrawal. Recovery requires professional medical detox followed by comprehensive addiction treatment. Encouraging the person toward professional help, not managing their addiction for them, is the most constructive role open to a family member.
- Consider a professional intervention: If the person is resistant to acknowledging the problem, a professionally facilitated intervention, led by a certified interventionist, is the next step. Our admissions team provides guidance on planning an intervention.
Where Can You Get Xanax Addiction Treatment in Tampa?
Effective treatment for Xanax addiction addresses both the physical and psychological dimensions of dependence.
The comprehensive treatment approach has 6 parts:
- Medically Supervised Detox: Xanax detox in Tampa requires medical oversight to manage withdrawal safely. Our clinical team uses evidence-based tapering protocols to minimize withdrawal discomfort and prevent dangerous complications, including seizures. Medical detox is the necessary foundation for Xanax recovery.
- Medication-Assisted Treatment (MAT): Medications prescribed and managed by our clinical team support stabilization during detox and early recovery, reducing cravings and withdrawal severity.
- Intensive Outpatient Program (IOP): For individuals who do not require residential treatment, our IOP provides structured therapeutic support while allowing you to maintain work, school, or family responsibilities. This is particularly relevant for working professionals with Xanax addiction who need treatment that fits their lives.
- Inpatient/Residential Treatment: A structured, supportive residential environment provides intensive care with 24-hour clinical supervision for individuals requiring a higher level of care.
- Dual Diagnosis Treatment: Xanax addiction co-occurs with the anxiety disorders it was prescribed to treat. Effective dual diagnosis treatment addresses both the addiction and the underlying mental health condition simultaneously. Treating anxiety without addressing the addiction, or addiction without addressing the anxiety, produces incomplete outcomes.
- Aftercare Planning: Recovery from benzodiazepine addiction is a process that extends beyond detox and primary treatment. Our aftercare planning ensures you have the support systems, community connections, and relapse prevention strategies needed for sustained recovery.
Contact Riverside Recovery of Tampa today if you or someone you love is showing signs of Xanax addiction in the Tampa Bay area. Our admissions team is available 24/7, and consultations are confidential and without obligation.
Frequently Asked Questions About Xanax Addiction
How can I tell if someone is on Xanax?
The most visible signs are the eyes, heavy lids, involuntary side to side eye movement, and a glazed, unfocused appearance. Other signs include slurred speech, slowed movement, unusual calm or drowsiness, memory problems, and mood changes. The signs are most pronounced during and shortly after intoxication.
What are the signs of Xanax addiction vs. normal prescription use?
Normal prescription use involves taking a prescribed dose at prescribed intervals with no dose escalation, no doctor shopping, no use of additional substances, and no functional impairment. Signs of addiction include taking more than prescribed, preoccupation with the drug supply, escalating doses, using to prevent rather than treat anxiety, functional decline at work or in relationships, and continuation despite negative consequences.
What do Xanax eyes look like?
Xanax eyes show heavy drooping eyelids, involuntary side to side eye movement, a glassy unfocused appearance and a fixed gaze. People call this presentation the “Xanax stare.” The overall effect is a half-awake, distant or blank look at any time of day. Pupil size stays normal, which separates benzodiazepine intoxication from opioid intoxication.
What does Xanax do to personality?
Regular Xanax use produces emotional blunting, reduced motivation, cognitive slowing, and increased irritability when the drug is wearing off. Long-term heavy use produces significant personality changes, including apathy, social withdrawal and cognitive impairment. Most of these effects are reversible with sustained abstinence.
Does Xanax change your personality permanently?
The personality and cognitive changes Xanax use produces reverse with abstinence, though recovery takes months to years for long-term heavy users. Whether prolonged high-dose benzodiazepine use produces lasting cognitive changes in a subset of users remains unresolved in the literature.
Can you tell if someone is addicted to Xanax if they have a prescription?
A prescription does not preclude addiction. There are 6 signs of addiction in someone holding a legitimate prescription. The person takes higher doses than prescribed, runs out early, and shows escalating anxiety when the drug wears off. Function deteriorates at work or in relationships, the person combines Xanax with alcohol, and preoccupation with maintaining supply grows.
What does Xanax do sexually?
Xanax reduces sex drive (libido), makes arousal more difficult, and causes erectile dysfunction in men and anorgasmia in women. The sexual effects are dose-dependent and improve with dose reduction or discontinuation.
Is Xanax addiction dangerous to stop on your own?
Yes. Xanax withdrawal produces seizures and death, particularly in people who stop abruptly after heavy, prolonged use. Medical supervision is required for safe Xanax discontinuation. Never stop Xanax suddenly without consulting a healthcare provider.
References
- American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 5th Edition: DSM-5. Arlington, VA: American Psychiatric Publishing; 2013.
- U.S. Food and Drug Administration. Alprazolam (Xanax) Prescribing Information. Silver Spring, MD: FDA.
- National Institute on Drug Abuse. Benzodiazepines and Opioids. Bethesda, MD: NIDA; Updated 2022. Available from: https://nida.nih.gov/research-topics/opioids/benzodiazepines-opioids
- Lader M. Benzodiazepines revisited, will we ever learn? Addiction. 2011 Dec;106(12):2086-2109. doi: 10.1111/j.1360-0443.2011.03563.x. PMID: 21714826.
- Tan KR, Rudolph U, Lüscher C. Hooked on benzodiazepines: GABA(A) receptor subtypes and addiction. Trends Neurosci. 2011 Apr;34(4):188-197. doi: 10.1016/j.tins.2011.01.004. PMID: 21353710; PMCID: PMC4020178.
- U.S. Food and Drug Administration. XANAX (alprazolam) tablets, prescribing information: adverse reactions. DailyMed, National Library of Medicine.


